In November 1953 American Airlines began the 1st regular non-stop commercial NY-LA air service with the Douglas DC7

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yesterdays airlines.com

  • 1932 First scheduled cross-country passenger flights with no change of plane
  • 1933 Transcontinental passenger flights in as little as 20 hours on the Boeing 247
  • 1934 First three-stop airline flights (TWA DC-2)
  • 1946 First one-stop airline flights (United DC-4 and TWA Constellation)
  • 1953 First sustained nonstop airline flights (TWA may have flown some LA-NY nonstops in 1947)

Source: Transcontinental flight – Wikipedia